Analytical method development and validation of Rasagiline mesylate in bulk and doasage form by UV spectroscopy
Abstract
A simple, rapid and precise uv spectroscopy method was developed for quantitative determination of rasagiline mesylate in bulk and dosage forms. This method was based on the beer’s lamberts law and The linearity was found to be in the concentration range of 50-300µg/ml and maximum absorbance was measured at 263nm 0.1m sulphuric acid as a solvent. The method was validated statistically and by recovery studies. Recovery was found to be in the range of 98 -102% and the %R.S.D was found to be less than 2%. The proposed method was economical and sensitive for the estimation of Rasagiline Mesylate (RM) in bulk and tablet dosage.
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