Role of cationic lipids for the formulation of lipoplexes

Authors

  • Varsha singh Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Plot No - 17-A, Greater Noida, Uttar Pradesh Author
  • Pramod Kumar Sharma Department of Pharmacy,School of Medical and Allied Sciences, Galgotias University, Plot No - 17-A, Greater Noida, Uttar Pradesh Author
  • Md. Aftab Alam Department of Pharmacy,School of Medical and Allied Sciences, Galgotias University, Plot No - 17-A, Greater Noida, Uttar Pradesh Author

DOI:

https://doi.org/10.33974/ijrpst.v1i1.1

Keywords:

Cationic lipids, lipoplexes, liposomes, non-immunogenic, transfection

Abstract

Cationic lipids are widely used for their advantages over viral gene transfer as they are non-immunogenic and their production is easy. The formation of cationic liposomes to lipoplexes with the help of cationic lipids has been done. Cationic lipids are often used in combination with helper lipids such as DOPE or cholesterol for defining their structural properties. The mode of lipoplex formation has been described in this review. This review also focuses on the parameters that affects the physico-chemical properties of lipoplexes describing their use for the cationic lipid based on the gene therapy purposes. The current status and various prospects for the transfection efficacy of lipoplexes is also been described.

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Published

23-03-2024

Issue

Vol. 1 No. 1 (2018): Volume 1 Issue 1

Section

Review Article

License

Copyright (c) 2024 Varsha singh, Pramod Kumar Sharma, Md. Aftab Alam (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

License Terms

This is an open-access article published in the International Journal of Research in Pharmaceutical Sciences and Technology (IJRPST) by Rubatosis Publications.

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How to Cite

Role of cationic lipids for the formulation of lipoplexes. (2024). International Journal of Research in Pharmaceutical Sciences and Technology, 1(1), 1-8. https://doi.org/10.33974/ijrpst.v1i1.1