Antimicrobial activity of microwave assisted synthesized chalcones and conventional synthesized chalcones: an overview

Abstract

A chalcone is a type of acetophenone in which one of the methyl hydrogens has been swapped out for a benzylidene group, making it a member of the class of chalcones. Kamboj*, et al has synthesized A fast and very rapid procedure is reported for the synthesis of chalcones from the ketones and aldehydes under microwave irradiation. All the synthesized compounds 1-28 were screened for their in vitro antibacterial and antifungal activities. All the compounds were tested for their antibacterial and antifungal activities by cup plate method. The structures of the compounds were confirmed by spectral data (infrared spectroscopy [IR] and 1H nuclear magnetic resonance [NMR]). All compounds showed excellent results against all fungi and are comparable to that of the standard antibiotic, Nystatin.